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  • The Ultimate 10-day Italy Itinerary: Discover the major cities in Italy with Trenitalia and Italo

    Klook Team
    Klook Team
    Last updated 8 Mar 2024
    10-day Italy Itinerary banner
    Looking for Italy itinerary ideas for your Italy vacation? Embark on an unforgettable Italian journey with the 2 train providers in Italy, Trenitalia and Italo!
    Whether you're a culture enthusiast, a history buff, or someone seeking the beauty of Italy's diverse landscapes, the classic Italy itinerary below offers a curated itinerary that embraces the essence of this enchanting country that will make your trip to Italy much easier! From the iconic landmarks of Rome and the artistic treasures of Florence to the sun-kissed Amalfi Coast and the romantic allure of Venice, our itinerary ideas ensure that every day is a new chapter in your Italian adventure. Immerse yourself in the rich history, savor the culinary delights, and discover hidden gems with our insightful day trips. Trust our expertise to unlock the secrets in this Italy trip itinerary, providing you with an authentic, immersive experience that goes beyond the ordinary, making your visit to Italy a journey of a lifetime. Follow our Italy travel guide and let the magic of this beautiful country unfold before you.

    Exploring the main stations of Italy

    Before jumping into Italy itinerary ideas, it's best to familiarize yourself with the main train stations in different cities. You'll encounter a network of stations, including a central train station in the heart of the city and often one or two additional stations in the suburbs.
    Aside from learning the main train station, you should choose the appropriate departing and arrival stations as it’s vital in avoiding inconvenience and unexpected detours! Central stations like Milan's Milano Centrale or Rome's Roma Termini, offer convenient access to the city's core attractions. For your easy reference in your Italy itinerary, here are some stations to remember:

    Central Stations

    Suburb Stations

    Milano Centrale

    Milano Porta Garibaldi

    Roma Termini

    Roma Tiburtina

    Roma Ostiense

    Florence Santa Maria Novella (also Firenze S.M. Novella / Firenze S.M.N)

    Firenze Campo di Marte

    Venezia S. Lucia

    Venezia Mestre

    Napoli Centrale

    Napoli Afragola

    Bologna Centrale

    Bologna Mazzini

    Palermo Centrale

    Messina Centrale

    Catania Centrale

    Understanding Italo vs. Trenitalia

    Understanding the differences between Italy’s two major train carriers, Italo and Trenitalia, is a must when planning your Italian getaway! These two major carriers offer distinct experiences in terms of pricing, service quality, and coverage.
    A red Italo train
    Italo, a more luxurious choice
    Seats inside a train
    Interior of Italo trains
    Known for its sleek, modern trains, Italo often caters to tourists seeking a more luxurious journey with amenities like free Wi-Fi, power outlets, and onboard entertainment. However, if you’re particular about budget, it’s best to keep in mind that ticket prices can be a bit higher.
    A red train
    Trenitalia is the primary train operator in Italy
    Meanwhile, the local train provider Trenitalia has a wider coverage network and ticket options, so it’s a more budget-friendly choice. When choosing between the two, consider your priorities — whether it's luxury and comfort or cost-efficiency.
    In terms of ticket classes, both offer various, each with its own perks. These distinctions encompass refund and exchange policies, seat and carriage amenities, and overall luxury. 
    First-class tickets often grant access to more comfortable seating, complimentary refreshments, and greater flexibility in changing travel plans. However, don’t get it wrong, second-class tickets are more budget-friendly and also provide a comfortable journey! 

    Ticket types

    Most Italian railways like Italo and Trenitalia offer four types of train tickets: first class (refundable), first class (with different conditions), second class (refundable), and second class (with different conditions). If you will be taking many separated train rides, consider getting point-to-point tickets which offer more flexibility!

    10-day itinerary in Italy: Ride the Rails with Italo and Trenitalia 

    10-day itinerary in Italy map
    Suggested 10-day itinerary in Italy

    Itinerary

    Route

    Train carrier

    Train duration

    Price in EUR

    Link to book

    Milan > Rome

    Italo, Trenitalia

    3 hours 30 mins

    From EUR 42 / adult

    Milan to Rome train

    Rome > Florence

    Italo, Trenitalia

    1 hour 30 mins

    From EUR 22 / adult

    Rome to Florence train

    Florence > Venice

    Italo, Trenitalia

    2 hours 15 mins

    From EUR 24 / adult

    Florence to Venice train

    Venice > Milan

    Italo, Trenitalia

    2 hours 30 mins

    From EUR 22 / adult

    Venice to Milan train

    Rome <> Naples / Amalfi Coast / Capri

    Italo, Trenitalia

    1 hour 30 mins

    From EUR 23 / adult

    Rome to Naples train

    Naples <> Pompeii

    Trenitalia

    30 mins

    From EUR 3 / adult

    Naples to Pompeii train

    Catania <> Palermo

    Trenitalia

    3 hours 30 mins

    From EUR 15 / adult

    Catania to Palermo train

    Day 1-2: Milan - the global fashion hub in Northern Italy

    Duomo di Milano in sunset
    Duomo di Milano in sunset
    Nestled in the Northern Italy, Milan stands as a testament to Italy's dynamic blend of history and contemporary elegance. At the city's core, the Duomo di Milano, an architectural marvel, reaches toward the heavens with its intricate spires and Gothic grandeur. Adjacent to this masterpiece, the Galleria Vittorio Emanuele II beckons with luxury, its historic corridors lined with high-end boutiques, cafes, and a palpable sense of refined sophistication. Milan's artistic richness further unfolds in Pinacoteca di Brera, a treasure trove of Italian Renaissance art, and in the breathtaking mural "The Last Supper," a testament to Leonardo da Vinci's genius.
    Milan's influence extends beyond art to the forefront of global fashion. The Fashion Quadrangle, a district synonymous with haute couture, showcases the world's leading designers and sets the stage for Milan Fashion Week, a globally recognized event that transforms the city into a mecca for style and innovation. Beyond the glamor, Milan offers serene respites in Parco Sempione, a sprawling oasis with picturesque paths, lakes, and the iconic Arco della Pace, providing a contrast to the bustling urban landscape.
    As dusk descends, Milan metamorphoses into a city of vibrant nightlife. The Navigli district, adorned with charming canals and trendy bars, pulses with energy, offering a lively backdrop for evenings filled with laughter and camaraderie. Milan's culinary scene, diverse and innovative, invites exploration from traditional trattorias serving authentic Lombard fare to avant-garde restaurants pushing the boundaries of gastronomy. Milan, a city where tradition and modernity converge seamlessly, invites visitors to immerse themselves in its rich tapestry of art, fashion, and cultural sophistication.

    Day 3-5: Rome - the “Eternal City"

    The Colosseum in Rome
    Explore the timeless beauty starting with the Colosseum in the heart of Rome
    Just a 3-hour train ride from Milan, you will arrive in Rome, the eternal city, a captivating tapestry of ancient history and modern vibrancy. At the heart of this iconic destination stands the Colosseum and Roman forum. The Colosseum was declared a World Heritage Site by UNESCO (unesco world heritage site) in 1980. Adjacent to this marvel, the Roman Forum and Palatine Hill offer a glimpse into the political and cultural center of ancient Rome. The Pantheon, a testament to architectural brilliance, invites visitors who visit Rome to marvel at its domed structure and artistic treasures.
    As day transitions to evening, Rome's modern flair comes to life in the vibrant neighborhoods of Trastevere and Campo de' Fiori. Cobblestone streets, lively markets, and traditional trattorias create a charming atmosphere that embodies the essence of Roman life. The Spanish Steps, adorned with azaleas in spring, offer a delightful spot for both locals and visitors to gather and enjoy the city's energy.
    Rome's culinary scene is a celebration of traditional Italian flavors. From authentic pasta dishes in local osterias to artisanal gelato savored on the steps of the Trevi Fountain, every bite is a sensory journey through Italy's gastronomic heritage. Rome, with its timeless allure and modern vibrancy, invites travelers to immerse themselves in a city where every corner whispers the stories of its rich past while embracing the pulse of contemporary life.
    St. Peter's Basilica in Vatican City
    Photo Credit: Anastasiya Lobanovskaya on Pexels
    St. Peter's Square in Vatican City
    St. Peter's Square in Vatican City
    Amidst the ancient splendors, Vatican City, an independent city-state within Rome, holds treasures such as St. Peter's Basilica and the Sistine Chapel, adorned with Michelangelo's masterpieces. The Vatican Museums house an extensive collection of art and artifacts, providing a journey through centuries of artistic expression. It is worth it to take a day trip to visit Vatican City from Rome.

    Day 6-7: Florence

    people walking through the busy streets in florence italy
    Photo Credit: Heidi Kaden on Unsplash
    Florence, cradled in the heart of Tuscany, is a city that encapsulates the essence of the Italian Renaissance. Renowned as the "Cradle of the Renaissance," Florence's historic city center is a living museum, where every cobblestone street, elegant piazza, and grand palazzo tells a story of art, culture, and intellectual enlightenment.
    At the city center you will find the Florence Cathedral, or Il Duomo di Firenze, with its iconic red dome dominating the skyline. The adjacent Baptistery and Giotto's Campanile complete the trio of architectural brilliance in Piazza del Duomo. Just steps away lies the Uffizi Gallery, a treasure trove of Renaissance masterpieces by artists such as Leonardo da Vinci, Michelangelo, and Botticelli. The Ponte Vecchio, a medieval bridge spanning the Arno River, is adorned with jewelry shops and offers stunning views of the city.
    Florence's artistic legacy extends beyond galleries to the Galleria dell'Accademia, home to Michelangelo's iconic David statue. The Medici Chapels, a testament to the powerful Medici family, showcase opulent mausoleums and intricate sculptures. Meanwhile, the Pitti Palace and its Boboli Gardens transport visitors to the grandeur of Renaissance court life.
    In addition to its artistic wealth, Florence is a culinary haven. The Mercato Centrale, a bustling food market, showcases Tuscan delights, from fresh produce to artisanal cheeses and cured meats. Traditional trattorias and enotecas line the streets, inviting visitors to savor the flavors of Chianti and indulge in classic dishes like ribollita and bistecca alla fiorentina.
    You may even take a day trip to the nearby town Pisa to see the famous Pisa tower!

    Day 8-10: Venice - the water city in Northern Italy

    Canals of Venice
    Photo Credit: nextvoyage on Pexels
    Venice, the "City of Canals" at Northern Italy, enchants with its unique charm as it rises gracefully from the Adriatic Sea. The heart of Venice, Piazza San Marco, boasts architectural marvels like St. Mark's Basilica and the Campanile, reflecting Byzantine and Renaissance influences. Navigating its labyrinthine canals reveals iconic landmarks such as the Rialto Bridge and the lively Rialto Market, where the city's pulse beats strongest.
    Beyond the tourist hubs, Venice's diverse neighborhoods, from the bohemian Dorsoduro to the historic Cannaregio, offer glimpses into local life. Art flourishes in venues like the Peggy Guggenheim Collection and the Accademia Galleries, while the Biennale di Venezia transforms the city into a contemporary art haven. You may also take a boat tour or gondola ride to enjoy the water city!
    From the main island in Venice, you can make a day trip to islands like Murano, renowned for its glassmaking heritage. Visitors are invited to explore its vibrant workshops where master artisans craft intricate glass pieces. Another choice for a day trip is Burano, a picturesque island celebrated for its charming, brightly-colored houses lined along narrow canals. Burano is not only a visual delight but also a fishing community known for its lace-making craftsmanship. Both Murano and Burano are great choices for a day trip!
    Person holding gelato
    Don't forget to grab a gelato as a treat to yourself!

    (Optional) Naples, Amalfi Coast, or Capri

    If your trip is longer than 10 days in Italy, we recommend that you further extend your trip to southern Italy. Naples, a city steeped in history and vibrant energy, unfolds along the stunning Bay of Naples in southern Italy. Home to iconic landmarks and a rich cultural heritage, Naples offers a captivating blend of ancient wonders and modern vivacity.
    Pizza on a table
    Napoli pizza are very tender, light, and moist at the same time!
    The historic center, a UNESCO World Heritage site, showcases Naples' ancient roots with landmarks like the Naples Cathedral, the Royal Palace of Naples, and the imposing Castel dell'Ovo overlooking the sea. The city's archaeological treasures are further revealed in the nearby ruins of Pompeii and Herculaneum, frozen in time by the eruption of Mount Vesuvius in 79 AD. Naples is also a culinary haven, renowned for its pizza and street food. The bustling Spaccanapoli, a narrow street that cuts through the historic center, is a gastronomic adventure, lined with pizzerias, trattorias, and vibrant markets. The Naples National Archaeological Museum houses an exceptional collection of Greco-Roman antiquities, including artifacts from Pompeii, offering a deeper understanding of the region's past.
    Looking for some day trips from Naples? Make sure you also take a day trip from Naples to the nearby archaeological site Pompeii! With just a 30-min train ride, you will arrive at a Roman city frozen in time by the eruption of Mount Vesuvius in 79 AD, Pompeii. Walking through its well-preserved streets and exploring its intricately detailed homes and public spaces is a haunting journey into the past, revealing the tragic yet captivating story of this once-thriving civilization. A day trip would be enough for you!
    Sculpture of Daedalus in Pompeii, Italy
    Sculpture of Daedalus in Pompeii, Italy
    The Amalfi Coast is also a good choice of day trip which takes you to a stretch of picturesque coastline in southern Italy. It is dazzled with dramatic cliffs, pastel-hued villages, and famous cities like Positano and Amalfi. Be ready for panoramic views of the Tyrrhenian Sea as well. Meanwhile, if you take a boat tour to Capri, you'll be delighted with a glamorous island in the Bay of Naples that captivates with its crystalline waters, limestone cliffs, and chic boutiques, creating a Mediterranean sea paradise that has long inspired artists, writers, and discerning travelers.
    An island in Italy
    Photo Credit: mikegiugliano on Pexels

    (Optional) Sicily: Heading to Southern Italy

    Looking for a southern Italy itinerary to enjoy more sunlight and beaches? You may end your Italy itinerary at Sicily, the largest island in Southern Italy that unfolds like a treasure trove of diverse landscapes, rich history, and culinary delights. From the bustling markets of Palermo to the ancient ruins of Agrigento, each corner reveals a layer of Sicily's storied past. The Valley of the Temples, a UNESCO World Heritage site, showcases remarkably preserved Greek ruins, inviting visitors to step back in time.
    A beach with blue waters
    Photo Credit: Daniele Putti on Pexels
    You can also take a day trip to the charming town of Taormina, perched atop a hill with views of Mount Etna and the Ionian Sea, captivates with its ancient Greek theater and vibrant atmosphere. Sicily's natural wonders include the formidable Mount Etna, Europe's most active volcano, where adventurous souls can hike its slopes or explore lava caves that is absolutely worth a day trip to go.
    Whether wandering through the historical marvels of Syracuse, relaxing on the stunning beaches of Cefalù, or savoring a granita in a quaint village square, ending your Italy itinerary with Sicily is all worth it! Sicily enchants with its blend of ancient allure and modern vibrancy, inviting travelers to immerse themselves in the captivating mosaic of this Mediterranean gem.

    Why should you consider taking trains to visit Italy?

    Visiting Italy by train has its own perks that will make your trip all the more enjoyable, which are: 
    Shorter travel time: Right off the bat, the shorter transfer time elevates the experience since train stations are usually in the city center, and easy access to major attractions is guaranteed. This means less time spent on the road to and from airports. Rental car is also a popular choice for Italy road trips, yet it takes a longer time to transfer from city to city compared to public transportation.
    Cost-effectiveness: Train travel is also cost-effective, with the caveat that early booking is key to securing lower ticket prices. For peak seasons like summer, booking at least four weeks in advance is recommended to take advantage of discounted fares. 
    #KlookTip: Train ticket prices can be 3x more expensive than the usual in peak season compared to off season. If you are more budget concerned, consider traveling in winter time!
    Travel without trouble: Moreover, train travel is hassle-free with e-tickets offered by many carriers, eliminating the need for pre-trip check-in, saving time, and reducing stress. This ease of redemption, coupled with various ticket pick-up options, simplifies the process for tourists.
    Spacious storage space: You can also rely on trains for the ample luggage space provided, especially for those with large or heavy bags. Unlike budget airlines that often charge exorbitant fees for additional luggage, trains offer more flexibility and comfort!

    Other transportations in Italy other than rail

    People on a bus
    For convenient city public transportation to visit Italy, there are regional and city train passes which offer great advantages. Though trains are a fantastic way to explore the heart of Italian cities, metro passes and airport bus services provide equal mobility and convenience for tourists! In major cities like Rome, Milan, and Venice, metro passes offer unlimited access to public transportation. It’s easier to navigate urban areas, reach attractions, and explore neighborhoods. 
    Airport buses such as the Fiumicino Airport - Rome Bus by SIT Bus Shuttle and Milan Malpensa Airport - Milan Bus by Terravision provide affordable, comfortable, and timely transfers between airports and city centers, complete with free Wi-Fi and professional service.
    Tourists can even visit Italy by various options like Milan city cards, Venice Waterbus passes (Vaporetto Pass), and Florence Hop-On Hop-Off Buses to enhance their city experiences. These products offer not only cost savings but also the flexibility to move around cities efficiently, ensuring you get the most out of your Italy itinerary. If you would like to enjoy private time with your special one in Venice, you should never miss the gondola ride in the city!
    With Italo and Trenitalia (and Klook!) as your trusted companions the entire trip, you'll not only experience the ease and comfort of rail travel visiting Italy but also experience the rich tapestry of Italy's cultural, historical, and artistic wonders in this Italy trip!
    What are you waiting for? Grab a train ticket now and follow this classic Italy itinerary and discover the beauty of Italy!

    Frequently Asked Questions

    1. What is the difference between first and second class tickets?

    First-class tickets typically offer more spacious seating, fewer passengers per carriage, and additional amenities like complimentary drinks and snacks. Second-class tickets provide a comfortable standard travel experience.

    2. Can I bring my luggage on trains in Italy?

    Yes, you can bring your luggage on trains. However, there are size and weight restrictions, and larger items may require a reservation. Check the specific rules for the train service you're using.

    3. How early should I arrive at the train station?

    Arriving at least 30 minutes before departure is recommended, especially if you need to collect tickets or have reserved seating.

    4. How do I navigate train stations in Italy?

    Train stations in Italy are generally well-signposted in both Italian and English. Look for departure boards, information desks, and platform signs to navigate your way easily.

    5. Are there food and beverage services on Italian trains?

    Yes, both first and second-class carriages often have a bar or trolley service where you can purchase snacks and drinks. Some longer routes may also have dining cars.

    6. Can I refund my bookings when there's a strike?

    Contact Klook Customer Support for refund or exchange in case you need any emergency services. You may need to provide proof of arrangement of alternative transportation, or flight/hotel cancellation upon carriers' requirements. Refunds may take 2-8 weeks.

    7. Do my Europe train tickets include seat reservations?

    Yes! International and domestic high speed trains ticket prices are inclusive of seat reservations. You will be automatically assigned a seat by the booking system.

    Book your Italy trip now!

    Gondola ride at Venice, Italy
    Photo Credit: adrian krajcar on Unsplash
    Feel free to adjust the number of days in your Italy itinerary to fit your interests! If you are only looking for a Northern Italy itinerary, you may combine Como (with Lake Como), Dolomites, Verona & Venice as your unique Northern Italy itinerary. If you prefer sun and beaches, combine southern cities in your itinerary! Book train tickets on Klook and start your Italy exploration now!

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