Where to?

Check-in/out dates

Select your dates

Guests and rooms

2 adults, 1 room

Find more hotels in Houston

Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG

9300 S Main StreetSee map

฿ 4,628.2per night

This is the cheapest price in 30 days, based on the rates on 5 Oct

Top reasons for booking
With a stay at Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG, you'll be centrally located in Houston, just a 3-minute walk from NRG Park and 14 minutes by foot from NRG Stadium. This hotel is 2.5 mi (4.1 km) from MD Anderson Cancer Center and 2.6 mi (4.2 km) from Rice University.
Popular facilities
Free WiFi
Fitness center
24-hour front desk
Luggage storage
Business center
Free parking
4.7/5Fantastic 1K+ reviews
Exploring the area
Stadium Park/Astrodome Station, 2.0km, About 32 mins from hotel by foot
Gare Saint-Lazare, 1.1km, About 19 mins from hotel by foot
William P Hobby Airport, 14.6km, About 17 mins from hotel by car
12
Standard Room
Bed type arranged at check-in

30.0 m²

11
Standard Room, 1 King Bed
1 double bed or bigger

30.0 m²

11
Standard Room, 2 Queen Beds
Bed type arranged at check-in

30.0 m²

14
Suite, 2 Queen Beds
Bed type arranged at check-in

35.0 m²

10
Suite, 1 King Bed
1 double bed or bigger

35.0 m²

7
Suite, 1 King Bed, Roll-in Shower (Communications)
1 double bed or bigger

35.0 m²

11
Suite, 2 Queen Beds, Accessible (Communications)
Bed type arranged at check-in

35.0 m²

10
Standard Room, 2 Queen Beds, Accessible Bathtub (Communications)
Bed type arranged at check-in

33.0 m²

8
Suite, 1 King Bed, Accessible (Communications)
1 double bed or bigger

35.0 m²

10
Suite, 2 Queen Beds, Accessible Bathtub (Communications)
Bed type arranged at check-in

35.0 m²

9
Standard Room, 1 King Bed, Accessible (Communications)
1 double bed or bigger
10
Standard Room, 2 Queen Beds, Accessible (Communications)
Bed type arranged at check-in
9
Standard Room, 1 King Bed, Roll-in Shower (Communications)
1 double bed or bigger
5
Room (Specialty)
1 single bed

Earn KlookCash for this booking & save on the next one

Reviews

Read all reviews
4.7/5.0

Fantastic

1K+ reviews
Location
0.0
Services offered
4.7
Cleanliness
4.7
Atmosphere & facilities
4.5
All
4.5+
3.0+
Alberto
Reviewed: 30 Jun 2026

4.0/5.0

Great

Stayed with friends

Location was good and the Staff very friendly! Property was basic and could use some updating in the rooms department. Other than that it worked for us.
Lisa
Reviewed: 28 Jun 2026

5.0/5.0

Fantastic

Stayed with family

Always consistent between the locations I visited in the US and Canada. Clean, spacious and has what I need if I forget something.
Diego
Reviewed: 27 Jun 2026

5.0/5.0

Fantastic

Stayed with kids

Good place to stay
Manuel
Reviewed: 27 Jun 2026

5.0/5.0

Fantastic

Solo stay

I really enjoy my stay at the Holiday Inn Express in Houston. The staff were very friendly, the place was very clean and fresh specially the bed, sheets and pillows. The room was clean and fresh also very cool temperature. Over all I had an awesome time atvthe hotel.
Katherine
Reviewed: 27 Jun 2026

5.0/5.0

Fantastic

Stayed with family · For friends and family

Great location for NRG stadium, clean lobby and rooms. Very spacious room. Great breakfast and pool.
Joanna
Reviewed: 24 Jun 2026

3.0/5.0

Good
Staff nice, facility somewhat clean. Breakfast marginal. Ants and dying cockroaches in toom.
Kenya
Reviewed: 23 Jun 2026

5.0/5.0

Fantastic

Stayed with family

I really enjoyed my stay. The property is within walking distance of NRG Stadium, and only about a 10 minute drive to my Doctors’ office in the medical center. There are also, several eating places near by, which are all pluses, but the most important thing for me was the great service. The staff were extremely nice, and wonderfully accommodating.
Kenneth
Reviewed: 21 Jun 2026

5.0/5.0

Fantastic

Stayed with partner

Clean throughout and front desk was friendly and helpful
Lars
Reviewed: 21 Jun 2026

3.0/5.0

Good

Stayed with kids

The hotel was greatly located for a game at NRG stadium. Their breakfast was decent. The rooms were spacious and clean. Unfortunately the staff was not very helpful. Despite several phone calls they still haven’t fixed an issue with my bill and they haven’t been responding to an item we left behind.
ARMEN
Reviewed: 20 Jun 2026

4.0/5.0

Great
Shower was not in good condition. Walls pilling off. Water pressure was low

Overview

Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG

Rooms:146
Floors:4
Star rating:

With a stay at Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG, you'll be centrally located in Houston, just a 3-minute walk from NRG Park and 14 minutes by foot from NRG Stadium. This hotel is 2.5 mi (4.1 km) from MD Anderson Cancer Center and 2.6 mi (4.2 km) from Rice University.

Description

With a stay at Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG, you'll be centrally located in Houston, just a 3-minute walk from NRG Park and 14 minutes by foot from NRG Stadium. This hotel is 2.5 mi (4.1 km) from MD Anderson Cancer Center and 2.6 mi (4.2 km) from Rice University.

See all

Exploring the area

Transport

Stadium Park/Astrodome Station

Metro stations
2.0km

Gare Saint-Lazare

Train stations
1.1km

William P Hobby Airport

Airports
14.6km

Attractions

NRG Stadium

1.2km

NRG Park

1.4km

NRG Astrodome

1.5km
See map

Facilities & services

Popular facilities
Free WiFi
Fitness center
24-hour front desk
Luggage storage
Business center
Free parking
General
Parking
Non-smoking throughout
Gift shop
Accessibility
Vending machine
Safety & security
Safety deposit box
Business facilities
Meeting facilities
Banquet facilities
Cleaning services
Laundry service
Reception services
ATM/Bank
Fast check-in
Fast check-out
Multilingual staff
Health & fitness
Outdoor Swimming pool
Accessibility
Wheelchair accessible
Wheelchair accessible parking
Food & drink
Free breakfast
See all facilities

Property policies

Check-in/out Time

Earliest check-in time:After 15:00 - Before 23:59

Latest check-out time:Before 12:00

Check-in policy

The guest responsible for check-in must be aged 21 or above

Special check-in instructions

Front desk staff will greet guests on arrival at the property. Information provided by the property may be translated using automated translation tools.

Check-in descriptions

Extra-person charges may apply and vary depending on property policy

Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges

Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed

This property accepts credit cards; cash is not accepted

Cashless transactions are available

Safety features at this property include a smoke detector

This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)

Note: Check-in policies vary by property. Please check carefully before booking

Child Policy

Children at all ages are welcome to stay at this property

Mandatory fees

You'll be asked to pay the following charges at the property. Fees may include applicable taxes:

Destination fee: USD 0.81 per accommodation, per night

We have included all charges provided to us by the property.

Other fees

Early check-in is available for a fee (subject to availability)

Late check-out is available for a fee (subject to availability)

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

Food & drinks

A complimentary continental breakfast is served on weekdays from 6:00 AM to 9:30 AM and on weekends from 6:30 AM to 10:00 AM.

See all policies

Stays nearby

1/5

InterContinental Houston by IHG

4.7/5
Fantastic
1K+ reviews
500m from TMC Transit Center,Houston
Fitness
Business center
฿8,314.4
Incl. taxes & fees: ฿8,314.4
1/5

Courtyard by Marriott Houston by the Galleria

4.2/5
Great
1K+ reviews
500m from The Galleria,Houston
Fitness
Business center
฿5,799.7
Incl. taxes & fees: ฿5,799.7
1/5

Haven Inn & Suites Downtown Houston

4.7/5
Fantastic
1K+ reviews
Houston
Hospitable service
฿2,470.8
Incl. taxes & fees: ฿2,470.8
1/5

Cambria Hotel Houston Downtown Convention Center

4.4/5
Great
1K+ reviews
1.1km from downtown,Houston
Fitness
฿9,372.3
Incl. taxes & fees: ฿9,372.3
1/5

Holiday Inn Express And Suites Pasadena Houston Southeast by IHG

4.3/5
Great
481 reviews
2.6km from downtown,Pasadena
Fitness
Business center
฿5,498.1
Incl. taxes & fees: ฿5,498.1
1/5

Hilton Garden Inn Houston/Galleria Area

4.3/5
Great
1K+ reviews
600m from Gerald D. Hines Waterwall Park,Houston
Fitness
Business center
฿4,470.3
Incl. taxes & fees: ฿4,470.3
1/5

AC Hotel by Marriott Houston Downtown

4.5/5
Fantastic
1K+ reviews
700m from downtown,Houston
Fitness
Business center
฿9,051.9
Incl. taxes & fees: ฿9,051.9
Home United States Houston Hotels in Houston Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG

Explore more on Klook

Top attractions in Houston

Everything you need for your Houston visit

Top destinations in United States