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Guests and rooms

2 adults, 1 room

The Chemists’ Club Hotel

52 E 41st StSee map

S$ 554.32per night

This is the cheapest price in 30 days, based on the rates on 4 Oct

Top reasons for booking
With a stay at The Chemists’ Club Hotel, you'll be centrally located in New York, within a 5-minute walk of Grand Central Terminal and 5th Avenue. This boutique hotel is 0.3 mi (0.4 km) from Bryant Park and 0.5 mi (0.8 km) from Rockefeller Center.
Popular facilities
Bar
Restaurant
Free WiFi
Fitness center
24-hour front desk
4.7/5Fantastic 480 reviews
Exploring the area
Grand Central - 42 St. Station, 200m, About 4 mins from hotel by foot
Grand Central Terminal, 300m, About 4 mins from hotel by foot
New York Skyports Incorporated Seaplane Base, 2.0km, About 4 mins from hotel by car
5
Classic Room, 1 King Bed
1 double bed or bigger

19.0 m²

5
Deluxe Room, 1 King Bed
1 double bed or bigger

28.0 m²

5
Deluxe Room, 1 Queen Bed
1 double bed or bigger

19.0 m²

5
Deluxe Room, 2 Double Beds
2 beds

33.0 m²

5
Deluxe Double Mobility/Hearing Accessible with Roll-In Shower
2 beds

33.0 m²

5
King Deluxe Mobility/Hearing Accessible with Roll-In Shower
1 double bed or bigger

33.0 m²

6
Junior Suite
2 beds

37.0 m²

6
Deluxe Room, 1 Queen Bed, Terrace
1 double bed or bigger

19.0 m²

5
Junior Suite King Mobility/Hearing Accessible with Transfer Shower
2 beds
5
Alchemy Suite
1 double bed or bigger

33.0 m²

5
King Deluxe Mobility/Hearing Accessible with Tub
1 double bed or bigger

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Read all reviews
4.7/5.0

Fantastic

480 reviews
Location
0.0
Services offered
4.8
Cleanliness
4.7
Atmosphere & facilities
4.6
All
4.5+
3.0+
Lynn
Reviewed: 13 Jun 2026

5.0/5.0

Fantastic

Solo stay

My new favorite in Midtown. Will definitely stay again.
zahi
Reviewed: 10 Jun 2026

5.0/5.0

Fantastic

Stayed with partner

Clean room, air conditioner
Elizabeth
Reviewed: 9 Jun 2026

5.0/5.0

Fantastic

Stayed with partner

The staff was very welcoming and the room was very clean. It’s in a great location, and we’ll definitely be back.
Eric
Reviewed: 8 Jun 2026

4.0/5.0

Great

Stayed with partner

The Chemist Club Hotel has so much going for it. It was clean, quiet, and located in an easy spot to get around the city. The room was good sized for New York and was surprisingly quiet as well- bonus that you can control the fan in the room to be on all the time. It is conveniently located about a block from Grand Central Station, so that made sightseeing really straightforward. The staff were all friendly, and it was nice we could leave our luggage with them when we arrived before check in time. I was disappointed that there weren’t quick breakfast options- I possibly misread the options about this ahead of time- especially since two mornings we had to leave right away and get to an event. Thankfully, there are quick options in Grand Central Station. Overall, we would stay here again.
Todd
Reviewed: 8 Jun 2026

3.0/5.0

Good
HVAC system was incredibly noisy, which interfered with our sleep. No iron in the room, bathroom very small, limited outlet access near bed.
eden
Reviewed: 8 Jun 2026

5.0/5.0

Fantastic

Stayed with family

This is a lovely boutique hotel centrally located. I could go on and on about how wonderful all the employees are here, so welcoming, and efficient. We have stayed twice, and always leave happy.
Jeffrey Thomas
Reviewed: 5 Jun 2026

3.0/5.0

Good

Solo stay

This review will vary depending on who the traveler is: if you want a reasonable rate, fantastic room and location, this is a 10/10; but if you need anything that a traditional hotel offers in the way of service or amenities, then I'd rate this a 5/10. Its 2026 and they still have a standard TV with outdated worthless cable channels and no ability to stream; no room service, no plates or utensils to use if you order food from a delivery service. Management of the hotel is seriously lacking - BUT that's not a knock on the actual hotel employees who were all A+ - the management company just doesn't staff the hotel so there's only a few employees on site. If you try calling the front desk, it may take 7-8 tries. Last complaint is the bogus resort fee they charge and justify by offering you a couple free sodas in the mini-fridge and some random snacks that I didn't even touch - hate any hotel that uses these gimmicks to give the appearance of a lower daily room rate and then tacks on these additional charges without any real purpose.
Vaheid
Reviewed: 5 Jun 2026

5.0/5.0

Fantastic

Solo stay

Friendly staff, clean facility, nice gym and good location
Carly
Reviewed: 4 Jun 2026

5.0/5.0

Fantastic

Stayed with friends

Very clean room; staff was super nice and helpful.
Margaret
Reviewed: 2 Jun 2026

5.0/5.0

Fantastic
Fabulous staff and unbeatable location right down from the NY Public Library. We loved it!
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