Where to?

Check-in/out dates

Select your dates

Guests and rooms

2 adults, 1 room

Find more hotels in Houston

Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG

9300 S Main StreetSee map

₱ 8,828.9per night

This is the cheapest price in 30 days, based on the rates on 16 Nov

Top reasons for booking
With a stay at Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG, you'll be centrally located in Houston, just a 3-minute walk from Reliant Park and 14 minutes by foot from Reliant Stadium. This hotel is 2.5 mi (4.1 km) from MD Anderson Cancer Center and 2.6 mi (4.2 km) from Rice University.
Popular facilities
Free WiFi
Fitness center
24-hour front desk
Luggage storage
Business center
4.7/5Fantastic 1K+ reviews
Exploring the area
Gare Saint-Lazare, 1.1km, About 19 mins from hotel by foot
William P Hobby Airport, 14.6km, About 17 mins from hotel by car
Stadium Park/Astrodome Station, 2.0km, About 32 mins from hotel by foot
15
Standard Room
Bed type arranged at check-in

30.0 m²

11
Standard Room, 1 King Bed
1 double bed or bigger

30.0 m²

11
Standard Room, 2 Queen Beds
Bed type arranged at check-in

30.0 m²

14
Suite, 2 Queen Beds
Bed type arranged at check-in

35.0 m²

10
Suite, 1 King Bed
1 double bed or bigger

35.0 m²

7
Suite, 1 King Bed, Roll-in Shower (Communications)
1 double bed or bigger

35.0 m²

11
Suite, 2 Queen Beds, Accessible (Communications)
Bed type arranged at check-in

35.0 m²

10
Standard Room, 2 Queen Beds, Accessible Bathtub (Communications)
Bed type arranged at check-in

33.0 m²

8
Suite, 1 King Bed, Accessible (Communications)
1 double bed or bigger

35.0 m²

10
Suite, 2 Queen Beds, Accessible Bathtub (Communications)
Bed type arranged at check-in

35.0 m²

9
Standard Room, 1 King Bed, Accessible (Communications)
1 double bed or bigger
10
Standard Room, 2 Queen Beds, Accessible (Communications)
Bed type arranged at check-in
9
Standard Room, 1 King Bed, Roll-in Shower (Communications)
1 double bed or bigger
5
Room (Specialty)
1 single bed

Earn KlookCash for this booking & save on the next one

Reviews

Read all reviews
4.7/5.0

Fantastic

1K+ reviews
Location
0.0
Services offered
4.7
Cleanliness
4.7
Atmosphere & facilities
4.6
All
4.5+
3.0+
Martha
Reviewed: 15 Aug 2026

5.0/5.0

Fantastic

Stayed with family · For friends and family

The hotel is spectacular! Clean, efficient, well maintained, awesome! Staff is so friendly and polite, very helpful and thoughtful! Breakfast was delicious and nutricious! Over the top experience! Looking forward to come back soon.
james
Reviewed: 13 Aug 2026

2.0/5.0

Below average

Stayed with partner

There were roaches in the bathroom! Never stayed at a Holiday Inn with roaches in the room. Unbelievable
Joseph
Reviewed: 13 Aug 2026

5.0/5.0

Fantastic

Stayed with partner

Always a great stay. Staff is helpful and friendly and the hotel is always clean and welcoming. Makes coming for medical much more pleasant.
Leigh
Reviewed: 12 Aug 2026

5.0/5.0

Fantastic

Stayed with family · For friends and family

Room was clean, parking was good. I recommend the property
Frances
Reviewed: 12 Aug 2026

5.0/5.0

Fantastic
The room was dark and the air conditioner created nice white noise. The staff was helpful and the free breakfast was good.
Jenni
Reviewed: 11 Aug 2026

3.0/5.0

Good

Stayed with partner

Entering the building, it is very impressive.—looks & smells clean. There was only one man at the desk and he was very cordial and professional but there was a long line to check in & I had to wait at least 15-20 minutes. The room was ok. First room we were in we could hear the people next door loud & clear as if they were in the room with us. We moved to the 2nd floor and had no problem with noise. The bathtub area had some areas that needed to be cleaned/Hair in toilet/Tissue box empty. Very disappointing that we found a pair of men’s underwear underneath the sink. We reported it before we checked out. We’ve stayed at this hotel for many years because it’s close to MD Anderson. Not sure I will go back.
Donald
Reviewed: 7 Aug 2026

5.0/5.0

Fantastic
Modern and clean for a great price! Plush beds, small seating area with sofa and table. Well maintained pool. Breakfast would be the only complaint… not many options and the items there seemed old- dry/stale. Overall, we would use this hotel again.
Kelly
Reviewed: 5 Aug 2026

5.0/5.0

Fantastic
Everything. It is near restaurants, the medical center and nrg
Keith
Reviewed: 2 Aug 2026

5.0/5.0

Fantastic
Nice and quiet! Really good location,close to NRG stadium.
Karina Yolanda
Reviewed: 31 Jul 2026

5.0/5.0

Fantastic
El televisor del cuarto no es smart tv

Overview

Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG

Rooms:146
Floors:4
Star rating:

With a stay at Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG, you'll be centrally located in Houston, just a 3-minute walk from Reliant Park and 14 minutes by foot from Reliant Stadium. This hotel is 2.5 mi (4.1 km) from MD Anderson Cancer Center and 2.6 mi (4.2 km) from Rice University.

Description

With a stay at Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG, you'll be centrally located in Houston, just a 3-minute walk from Reliant Park and 14 minutes by foot from Reliant Stadium. This hotel is 2.5 mi (4.1 km) from MD Anderson Cancer Center and 2.6 mi (4.2 km) from Rice University.

See all

Exploring the area

Transport

Gare Saint-Lazare

Train stations
1.1km

William P Hobby Airport

Airports
14.6km

Attractions

Stadium Park/Astrodome Station

2.0km

NRG Stadium

1.2km

NRG Park

1.4km

NRG Astrodome

1.5km
See map

Facilities & services

Popular facilities
Free WiFi
Fitness center
24-hour front desk
Luggage storage
Business center
General
Parking
Parking (additional charge)
Non-smoking throughout
Gift shop
Accessibility
Vending machine
Safety & security
Safety deposit box
Business facilities
Meeting facilities
Banquet facilities
Cleaning services
Laundry service
Reception services
ATM/Bank
Fast check-in
Fast check-out
Multilingual staff
Health & fitness
Outdoor Swimming pool
Accessibility
Wheelchair accessible
Wheelchair accessible parking
Food & drink
Free breakfast
See all facilities

Property policies

Check-in/out Time

Earliest check-in time:After 15:00

Latest check-out time:Before 12:00

Check-in policy

The guest responsible for check-in must be aged 21 or above

Special check-in instructions

Front desk staff will greet guests on arrival at the property. Information provided by the property may be translated using automated translation tools.

Check-in descriptions

Extra-person charges may apply and vary depending on property policy

Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges

Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed

This property accepts credit cards; cash is not accepted

Cashless transactions are available

Safety features at this property include a smoke detector

This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)

Note: Check-in policies vary by property. Please check carefully before booking

Child Policy

Children at all ages are welcome to stay at this property

Mandatory fees

You'll be asked to pay the following charges at the property. Fees may include applicable taxes:

Destination fee: USD 0.81 per accommodation, per night

We have included all charges provided to us by the property.

Other fees

Self parking fee: USD 7.00 per day

Early check-in is available for a fee (subject to availability)

Late check-out is available for a fee (subject to availability)

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

Food & drinks

A complimentary continental breakfast is served on weekdays from 6:00 AM to 9:30 AM and on weekends from 6:30 AM to 10:00 AM.

See all policies
Home United States Houston Hotels in Houston Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG

Explore more on Klook

Everything you need for your Houston visit