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Guests and rooms

2 adults, 1 room

21C Museum Hotel St Louis

1528 Locust streetSee map

₫ 4,363,868per night

This is the cheapest price in 30 days, based on the rates on 15 Oct

Top reasons for booking
Great view
Most user reviews comment positively on the view from their room
Popular facilities
Bar
Coffee shop
Restaurant
Free WiFi
Fitness center
Spa
4.5/5Fantastic 2K+ reviews
Exploring the area
Union Station - West Lot, 800m, About 13 mins from hotel by foot
St. Louis Union Station, 500m, About 9 mins from hotel by foot
Lambert–St. Louis International Airport, 18.9km, About 22 mins from hotel by car
7
Deluxe Room, 1 King Bed
1 double bed or bigger

29.0 m²

8
Luxury Double Room, 2 Queen Beds
Bed type arranged at check-in

39.0 m²

4
Room (Bunk Bed)
1 single bed

22.0 m²

4
Loft, 2 Queen Beds
Bed type arranged at check-in

40.0 m²

2
Deluxe Room, Accessible (Accessible)
1 double bed or bigger

25.0 m²

5
Suite, 1 King Bed (21C)
1 double bed or bigger

104.0 m²

3
Suite, 1 King Bed (Library)
1 double bed or bigger

68.0 m²

City view

4
Luxury Suite, 1 King Bed
1 double bed or bigger

51.0 m²

3
Deluxe Room, 1 Double Bed, Accessible
1 double bed or bigger

36.0 m²

2
Deluxe Suite, 1 Double Bed, Accessible
1 double bed or bigger

48.0 m²

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Read all reviews
4.5/5.0

Fantastic

2K+ reviews
Location
0.0
Services offered
4.5
Cleanliness
4.6
Atmosphere & facilities
4.5
All
4.5+
3.0+
Dawn
Reviewed: 1 Jul 2026

4.0/5.0

Great

Stayed with family

Very friendly staff, the room was very nice. We did enjoy our stay
Jennifer
Reviewed: 1 Jul 2026

3.0/5.0

Good

Stayed with partner

The room was dirty behind the door. A dirty coffee cup was used to hold the sugars and creamers. Only 1 cup ( which was that cup) was in the room. The 2nd night we didn't have a bath mat or extra toilet paper. We had to go to the front desk ask 10:30p to get toilet paper. The front desk acted annoyed at our request. The hotel was beautiful. The bartenders and valet guys were the friendliest. We were checking out at 630a on the 3rd day... valet wasn't open yet so we had to go to the front desk. The lady was rude and very irritated that she had to look for our keys, walk across the street and open the gate herself so we could get our car out. We didn't feel safe walking in the neighborhood. There were homeless people EVERYWHERE at dusk. Asking for money and making weird comments. The museum was in the middle of redoing the art so that was bare. The bed was much firmer than I prefer but that's just a personal preference. The breakfast was good.
Toshie
Reviewed: 30 Jun 2026

5.0/5.0

Fantastic

Stayed with partner

The bar was very good. Bartenders pay great attention to prepare each cocktails with perfections and these menus are amazingly creative. Breakfast was good, but it took over an hour to arrive. So it may not be for busy people. The room for the breakfast (cafeteria) seems too small while lobby and restaurant are much spacious.
T.
Reviewed: 29 Jun 2026

5.0/5.0

Fantastic

Solo stay

Excellent Would highly recommend to others. Also recommend staying at the Hilton at union station.
Maureen
Reviewed: 29 Jun 2026

5.0/5.0

Fantastic

Stayed with friends

We liked everything about this hotel! The artwork all over the hotel is beautiful and then you have the art museum on the entire 2nd floor. We used the pool, gym and steam room daily during our stay. The bar has a nightly bourbon pour after 8pm and a lovely multi level outdoor patio. The staff was friendly and helpful at all times as we always had questions! 5 stars. 10/10.
James M.
Reviewed: 27 Jun 2026

4.0/5.0

Great

Stayed with friends

Great place to stay!
Clarissa
Reviewed: 26 Jun 2026

2.0/5.0

Below average

Stayed with friends · For friends and family

Great Look, Major Security and Service IssuesThe hotel looks amazing, but the service, maintenance, and security were highly disappointing.Security: Returned to find my room completely unlocked and unattended after requesting room service. I had to go to the front desk to resolve it.Check-In: Overcharged for an early check-in fee beyond the agreed amount.Room: Shower dispensers were broken off the wall, unsightly, and empty.Housekeeping: Day two bed was made incorrectly; housekeeper took a tip to fix it but never returned.Dining: Restaurant server was rude and brought wrong utensils.Patio: Sat for an hour with zero service next to previous guests' dirty drinks.Note: I am still awaiting a response from management regarding these issues.
Mark
Reviewed: 26 Jun 2026

3.0/5.0

Good

Stayed with partner

First time I've stayed at a hotel where there wasn't complimentary coffee and or water. The bar service sucked and the prices for everything including the coffee was too much. I won't stay there again!
David
Reviewed: 25 Jun 2026

1.0/5.0

Below average

Solo stay

The A/C in my room would not cool the room. The maintenance person came to look at it, left and never returned. Lukewarm water for the shower. Non-existent staff to assist. The location is poor; 20 minute walk to downtown, with no restaurants or attractions nearby. Breakfast in the hotel restaurant was over priced and average at best. I would not recommend this hotel to anyone.
nathan
Reviewed: 25 Jun 2026

5.0/5.0

Fantastic

Stayed with family

We loved how quiet our room was. The breakfast was wonderful. The athletic club was a hit with the kids. It was so nice to have a restaurant right there and we loved moving the penguins around. Is definitely stay there again.